# Spatiotemporal dynamic evolution of the tumor microenvironment during neoadjuvant immunotherapy for bladder cancer

Source: [cell.com](https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(26)00557-4?rss=yes) · 2026-11-06 · Medicine
Page: https://themorning.science/story/spatiotemporal-dynamic-evolution-of-the-tumor-microenvironment-during-neoadjuvan-6e1aec1c4c866023

Hu et al. map phenotypic evolution of the bladder cancer microenvironment during neoadjuvant immunotherapy. Treatment drives divergent tumor cell fates, establishes an immunotherapy-induced tumor-myeloid barrier, promotes terminal T cell exhaustion, and induces a senescent iCAF…

## Coverage

- [Spatiotemporal dynamic evolution of the tumor microenvironment during neoadjuvant immunotherapy for bladder cancer](https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(26)00557-4?rss=yes) — cell.com, 2026-11-06

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