# Somatic mosaicism and longitudinal genotype-phenotype spectrum of ARR3-associated early-onset myopia in seven families

Source: [Biological sciences : nature.com subject feeds](https://www.nature.com/articles/s10038-026-01527-1) · 2026-11-11 · Life
Page: https://themorning.science/story/somatic-mosaicism-and-longitudinal-genotype-phenotype-spectrum-of-arr3-associate-7e6ae3e99235ddfd
Kind: research · Impact: low

## In brief

- A study reports somatic mosaicism in ARR3-associated early-onset myopia.
- The study covers seven families and describes a longitudinal genotype-phenotype spectrum.
- The source provided contains only the headline and feed listing, so details beyond these are not available.

## Why it matters

It adds clinical and genetic detail on how an ARR3 variant can present in early-onset myopia, which may help researchers interpret genotype-phenotype relationships in inherited myopia.

## Coverage

- [Somatic mosaicism and longitudinal genotype-phenotype spectrum of ARR3-associated early-onset myopia in seven families](https://www.nature.com/articles/s10038-026-01527-1) — Biological sciences : nature.com subject feeds, 2026-11-11

Tags: myopia, arr3, somatic mosaicism, genetics, early-onset myopia

---

Brief generated by AI (claude-haiku-5-5) from the reporting listed under Coverage. Headlines belong to their publishers. The Morning Science – https://themorning.science