# Self-amplifying RNA vaccines encoding chimeric and mosaic hemagglutinins confer immunity against phylogenetically diverse influenza A viruses

Source: [cell.com](https://www.cell.com/cell-reports/fulltext/S2211-1247(26)01323-9?rss=yes) · 2026-11-06 · Life
Page: https://themorning.science/story/self-amplifying-rna-vaccines-encoding-chimeric-and-mosaic-hemagglutinins-confer-358af8717e840c50

Seasonal influenza vaccines require annual reformulation and offer limited protection. Abbad et al. show that self-amplifying mRNA vaccines encoding chimeric and mosaic hemagglutinins elicit broadly protective antibodies against diverse influenza A virus strains, acting largely…

## Coverage

- [Self-amplifying RNA vaccines encoding chimeric and mosaic hemagglutinins confer immunity against phylogenetically diverse influenza A viruses](https://www.cell.com/cell-reports/fulltext/S2211-1247(26)01323-9?rss=yes) — cell.com, 2026-11-06

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