# Researchers identify DNA marker that could predict treatment response in myelodysplastic syndromes

Source: [Medical Xpress - latest medical and health news stories](https://medicalxpress.com/news/2026-11-dna-marker-treatment-response-myelodysplastic.html) · 2026-11-10 · Medicine
Page: https://themorning.science/story/researchers-identify-dna-marker-that-could-predict-treatment-response-in-myelody-51f656de56efbbd1
Kind: research · Impact: medium

## In brief

- A multicenter study reports that DNA methylation patterns present at diagnosis may help predict which myelodysplastic syndrome (MDS) patients will respond to azacitidine.
- The finding comes from a new study involving researchers at Sylvester Comprehensive Cancer Center, according to a Medical Xpress report dated 2026-11-10.

## Why it matters

If validated, a diagnostic methylation marker could help clinicians decide earlier which MDS patients are likely to benefit from azacitidine, a standard hypomethylating therapy.

## Timeline

- 2026-11-10: Medical Xpress reports the multicenter study findings on DNA methylation as a predictor of azacitidine response in MDS

## Coverage

- [Researchers identify DNA marker that could predict treatment response in myelodysplastic syndromes](https://medicalxpress.com/news/2026-11-dna-marker-treatment-response-myelodysplastic.html) — Medical Xpress - latest medical and health news stories, 2026-11-10

Tags: myelodysplastic syndromes, azacitidine, dna methylation, biomarkers, cancer treatment

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Brief generated by AI (claude-haiku-5-5) from the reporting listed under Coverage. Headlines belong to their publishers. The Morning Science – https://themorning.science