# Psychedelics show anti-inflammatory effects in sick animals but not healthy ones, meta-analysis finds

Source: [PsyPost – Psychology News](https://www.psypost.org/psychedelics-show-anti-inflammatory-effects-in-sick-animals-but-not-healthy-ones-meta-analysis-finds/) · 2026-11-13 · Mind
Page: https://themorning.science/story/psychedelics-show-anti-inflammatory-effects-in-sick-animals-but-not-healthy-ones-2945dcba24518cf9
Kind: research · Impact: medium

## In brief

- A systematic review and meta-analysis of laboratory and animal studies found that most report anti-inflammatory effects of psychedelics.
- The effects appear mainly when inflammation is already present, according to the review.
- In mice and rats, psychedelics reduced inflammatory markers in animals with induced inflammation.

## Why it matters

The findings suggest that anti-inflammatory effects reported in preclinical psychedelic research may depend on whether inflammation is already present, so results from induced-inflammation models may not apply to healthy subjects.

## Coverage

- [Psychedelics show anti-inflammatory effects in sick animals but not healthy ones, meta-analysis finds](https://www.psypost.org/psychedelics-show-anti-inflammatory-effects-in-sick-animals-but-not-healthy-ones-meta-analysis-finds/) — PsyPost – Psychology News, 2026-11-13

Tags: psychedelics, inflammation, meta-analysis, animal-studies, pharmacology

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Brief generated by AI (claude-haiku-5-5) from the reporting listed under Coverage. Headlines belong to their publishers. The Morning Science – https://themorning.science