# PANGEA: an integrated cell atlas across diverse biological contexts enables systematic profiling of multicellular responses in human diseases

Source: [nature.com](https://www.nature.com/articles/s41592-026-03295-4) · 2026-11-12 · Life
Page: https://themorning.science/story/pangea-an-integrated-cell-atlas-across-diverse-biological-contexts-enables-syste-3fa60df9a85a0cb1
Kind: research · Impact: medium

## In brief

- PANGEA is described as a single-cell transcriptomic atlas covering 160 human diseases across 48 organs.
- The work was published online in Nature Methods on 12 November 2026 (doi:10.1038/s41592-026-03295-4).
- The atlas is intended to enable systematic profiling of multicellular responses in human diseases.

## Why it matters

A single integrated atlas spanning many diseases and organs lets researchers compare cell-level responses across conditions rather than within isolated studies.

## Timeline

- 2026-11-12: PANGEA integrated cell atlas published online in Nature Methods

## Coverage

- [PANGEA: an integrated cell atlas across diverse biological contexts enables systematic profiling of multicellular responses in human diseases](https://www.nature.com/articles/s41592-026-03295-4) — nature.com, 2026-11-12

Tags: single-cell, transcriptomics, cell atlas, human disease, multicellular responses

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Brief generated by AI (claude-haiku-5-5) from the reporting listed under Coverage. Headlines belong to their publishers. The Morning Science – https://themorning.science