# Non-overlapping rather than “opposing” effects of microglial and macrophagic C3ar1 signaling

Source: [nature.com](https://www.nature.com/articles/s41380-026-03961-1) · 2026-11-11 · Mind
Page: https://themorning.science/story/non-overlapping-rather-than-opposing-effects-of-microglial-and-macrophagic-c3ar1-e0ddae39b0d2e6b7
Kind: research · Impact: medium

## In brief

- The study was published online in Molecular Psychiatry on 11 November 2026 (doi:10.1038/s41380-026-03961-1).
- The paper reports that microglial and macrophagic C3ar1 signalling have non-overlapping rather than opposing effects.
- The sources provided contain only the article's title and publication details, so no further findings can be reported.

## Why it matters

It suggests that C3ar1 signalling in microglia and in macrophages should be studied as separate processes, since the two cell types may not act in opposition.

## Timeline

- 2026-11-11: Published online in Molecular Psychiatry

## Coverage

- [Non-overlapping rather than “opposing” effects of microglial and macrophagic C3ar1 signaling](https://www.nature.com/articles/s41380-026-03961-1) — nature.com, 2026-11-11

Tags: microglia, macrophages, c3ar1, complement signalling, neuroimmunology

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Brief generated by AI (claude-haiku-5-5) from the reporting listed under Coverage. Headlines belong to their publishers. The Morning Science – https://themorning.science