# Microbiome-antibiotic-immune interactions influence mortality in preterm infant gut microbiota-humanized gnotobiotic mice

Source: [cell.com](https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(26)00578-1?rss=yes) · 2026-11-10 · Medicine
Page: https://themorning.science/story/microbiome-antibiotic-immune-interactions-influence-mortality-in-preterm-infant-3d49518cf96289d5
Kind: research · Impact: low

## In brief

- Schwartz et al. studied gnotobiotic mouse pups colonized with stool from preterm infants.
- The study reports associations between antibiotic administration, systemic immune responses, microbiome composition, and death in these mice.
- The findings are associative and come from a mouse model.

## Why it matters

Antibiotic use is common in preterm infants, and this work links antibiotics, immune responses and gut microbiome composition with mortality in a humanized mouse model, which could guide future research on neonatal care.

## Timeline

- 2026-11-10: Study published in Cell Reports Medicine

## Coverage

- [Microbiome-antibiotic-immune interactions influence mortality in preterm infant gut microbiota-humanized gnotobiotic mice](https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(26)00578-1?rss=yes) — cell.com, 2026-11-10

Tags: preterm infants, gut microbiome, antibiotics, immunity, mouse models

---

Brief generated by AI (claude-haiku-5-5) from the reporting listed under Coverage. Headlines belong to their publishers. The Morning Science – https://themorning.science