# Learning-associated flexibility of cortical taste coding is impaired in Shank3 knockout mice

Source: [eLife: latest articles](https://elifesciences.org/articles/108988) · 2026-11-12 · Life
Page: https://themorning.science/story/learning-associated-flexibility-of-cortical-taste-coding-is-impaired-in-shank3-k-074ebeba67270397
Kind: research · Impact: low

## In brief

- A study in eLife reports that Shank3 knockout mice show impaired learning-associated flexibility in cortical taste coding.
- The source is a short excerpt; the abstract frames the question of whether sensory processing defects in autism spectrum disorders impair flexible sensory encoding.

## Why it matters

Shank3 mutations are a model for autism spectrum disorders, and the study suggests sensory processing deficits in such models may extend to how the brain updates sensory meaning through learning.

## Timeline

- 2026-11-12: eLife published the article Learning-associated flexibility of cortical taste coding is impaired in Shank3 knockout mice

## Coverage

- [Learning-associated flexibility of cortical taste coding is impaired in Shank3 knockout mice](https://elifesciences.org/articles/108988) — eLife: latest articles, 2026-11-12

Tags: neuroscience, autism, taste coding, shank3, sensory processing

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Brief generated by AI (claude-haiku-5-5) from the reporting listed under Coverage. Headlines belong to their publishers. The Morning Science – https://themorning.science