# Identification of the SNHG14/hsa-miR-577/CLIC4 ceRNA axis reveals the association of CLIC4 with stromal activation and microenvironment remodeling in colorectal cancer

Source: [Biological sciences : nature.com subject feeds](https://www.nature.com/articles/s41598-026-79699-1) · 2026-11-10 · Life
Page: https://themorning.science/story/identification-of-the-snhg14-hsa-mir-577-clic4-cerna-axis-reveals-the-associatio-e69128ed22caae6d
Kind: research · Impact: low

## In brief

- The study identifies a SNHG14/hsa-miR-577/CLIC4 competing endogenous RNA (ceRNA) axis in colorectal cancer.
- The authors report an association between CLIC4 and stromal activation.
- The authors also link CLIC4 to microenvironment remodeling in colorectal cancer.

## Why it matters

It proposes a molecular link between a non-coding RNA network and tumour stroma in colorectal cancer, which may guide further mechanistic and biomarker research.

## Timeline

- 2026-11-10: Study listed in nature.com subject feeds

## Coverage

- [Identification of the SNHG14/hsa-miR-577/CLIC4 ceRNA axis reveals the association of CLIC4 with stromal activation and microenvironment remodeling in colorectal cancer](https://www.nature.com/articles/s41598-026-79699-1) — Biological sciences : nature.com subject feeds, 2026-11-10

Tags: colorectal-cancer, cerna, lncrna, tumor-microenvironment, stromal-activation, clic4

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Brief generated by AI (claude-haiku-5-5) from the reporting listed under Coverage. Headlines belong to their publishers. The Morning Science – https://themorning.science