# Found: a protein that drives ageing without unleashing inflammation

Source: [nature.com](https://www.nature.com/articles/d41586-026-03638-3) · 2026-11-12 · Life
Page: https://themorning.science/story/found-a-protein-that-drives-ageing-without-unleashing-inflammation-b99b3bf0ad66bc14
Kind: research · Impact: medium

## In brief

- In aged mice engineered to lack granzyme K, heart and liver function improved.
- These mice also showed less kidney damage than aged mice with the protein.
- The source describes granzyme K as a protein that drives ageing without unleashing inflammation.

## Why it matters

The findings point to granzyme K as a possible target for interventions aimed at age-related organ decline, though the evidence so far comes from mice.

## Timeline

- 2026-11-12: Study published online in Nature

## Coverage

- [Found: a protein that drives ageing without unleashing inflammation](https://www.nature.com/articles/d41586-026-03638-3) — nature.com, 2026-11-12

Tags: ageing, granzyme k, mice, inflammation, heart, liver

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Brief generated by AI (claude-haiku-5-5) from the reporting listed under Coverage. Headlines belong to their publishers. The Morning Science – https://themorning.science