# Flow-dependent TGF-β1 secretion from HCT116 cells following constriction-based microfluidic passage

Source: [Biological sciences : nature.com subject feeds](https://www.nature.com/articles/s41598-026-69804-9) · 2026-11-10 · Life
Page: https://themorning.science/story/flow-dependent-tgf-1-secretion-from-hct116-cells-following-constriction-based-mi-1eebfc68f16a8bc9
Kind: research · Impact: low

## In brief

- Study reports that HCT116 cells secrete TGF-β1 in a flow-dependent manner after passing through a constriction-based microfluidic device.
- The headline and feed entry provide no further details on methods, sample size, or quantitative results.

## Why it matters

It describes how mechanical stress from passing through narrow channels may change cytokine release by cancer cells, which matters for researchers using microfluidic cell handling or studying TGF-β signalling.

## Coverage

- [Flow-dependent TGF-β1 secretion from HCT116 cells following constriction-based microfluidic passage](https://www.nature.com/articles/s41598-026-69804-9) — Biological sciences : nature.com subject feeds, 2026-11-10

Tags: microfluidics, tgf-beta, mechanobiology, cell-signaling, cancer-cells

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Brief generated by AI (claude-haiku-5-5) from the reporting listed under Coverage. Headlines belong to their publishers. The Morning Science – https://themorning.science