# expert reaction to study in mice suggesting high-fat diet may increase risk of colon cancer through changes in intestinal stem cells

Source: [Science Media Centre](https://www.sciencemediacentre.org/expert-reaction-to-study-in-mice-suggesting-high-fat-diet-may-increase-risk-of-colon-cancer-through-changes-in-intestinal-stem-cells/) · 2026-11-12 · Science & Society
Page: https://themorning.science/story/expert-reaction-to-study-in-mice-suggesting-high-fat-diet-may-increase-risk-of-c-298cf7060a753cd0
Kind: research · Impact: medium

## In brief

- A study in mice published in Stem Cell Reports found that a high-fat diet leaves lasting changes in intestinal stem cells.
- Researchers at Arizona State University report that these changes could potentially increase the risk of tumor development in the colon.
- The findings come from mouse research, and an expert from King's College London described it as an interesting mechanistic study.

## Why it matters

The study offers a mechanistic link between diet and changes in intestinal stem cells that may relate to colon cancer risk, which can inform future research, though the evidence comes from mice and does not establish the same effect in humans.

## Coverage

- [expert reaction to study in mice suggesting high-fat diet may increase risk of colon cancer through changes in intestinal stem cells](https://www.sciencemediacentre.org/expert-reaction-to-study-in-mice-suggesting-high-fat-diet-may-increase-risk-of-colon-cancer-through-changes-in-intestinal-stem-cells/) — Science Media Centre, 2026-11-12
- [High-fat diet may increase colon cancer risk by changing intestinal stem cells](https://medicalxpress.com/news/2026-11-high-fat-diet-colon-cancer.html) — Medical Xpress - latest medical and health news stories, 2026-11-12

Tags: colon cancer, high-fat diet, intestinal stem cells, mice, diet and cancer

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