# Efficient and accurate mixed model association tool for single-cell eQTL analysis

Source: [nature.com](https://www.nature.com/articles/s41588-026-02798-2) · 2026-11-06 · Life
Page: https://themorning.science/story/efficient-and-accurate-mixed-model-association-tool-for-single-cell-eqtl-analysi-e6ba1e1f10da80dd

Nature Genetics, Published online: 06 November 2026; doi:10.1038/s41588-026-02798-2 SAIGE-QTL is a framework for eQTL mapping that directly models single-cell read counts using a Poisson mixed model, achieving improved statistical efficiency and power and enabling rare variant…

## Coverage

- [Efficient and accurate mixed model association tool for single-cell eQTL analysis](https://www.nature.com/articles/s41588-026-02798-2) — nature.com, 2026-11-06

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