# A trapped catalytic product acts as molecular glue for innate immune signalosome assembly

Source: [science.org](https://www.science.org/doi/abs/10.1126/science.aef3150?af=R) · 2026-11-12 · Life
Page: https://themorning.science/story/a-trapped-catalytic-product-acts-as-molecular-glue-for-innate-immune-signalosome-24212637f5d08337
Kind: research · Impact: medium

## In brief

- A Science paper reports that a trapped catalytic product acts as a molecular glue for innate immune signalosome assembly.
- The article is listed in Science, Volume 394, Issue 6825, November 2026.
- The source provides only the title and bibliographic details, so the mechanism and experimental findings are not described here.

## Why it matters

The finding describes how a small molecule produced by an enzyme may promote assembly of innate immune signalling complexes, which could inform how immune signalling is understood and studied.

## Timeline

- 2026-11-12: Article published in Science (Volume 394, Issue 6825)

## Coverage

- [A trapped catalytic product acts as molecular glue for innate immune signalosome assembly](https://www.science.org/doi/abs/10.1126/science.aef3150?af=R) — science.org, 2026-11-12

Tags: innate immunity, molecular glue, signalosome, immune signalling, catalysis

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Brief generated by AI (claude-haiku-5-5) from the reporting listed under Coverage. Headlines belong to their publishers. The Morning Science – https://themorning.science