# A single-cell lung cancer atlas reveals cellular and molecular drivers of metastasis and clinical outcome

Source: [nature.com](https://www.nature.com/articles/s43018-026-01260-w) · 2026-11-12 · Medicine
Page: https://themorning.science/story/a-single-cell-lung-cancer-atlas-reveals-cellular-and-molecular-drivers-of-metast-9be65d4afe5e4633
Kind: research · Impact: medium

## In brief

- A multicenter single-nucleus RNA sequencing atlas of lung cancer was published in Nature Cancer on 12 November 2026.
- The atlas combines single-nucleus RNA sequencing with spatial transcriptomics and clinical outcome data.
- The authors report cancer–host cell interactions linked to metastasis and clinical outcome.

## Why it matters

The study links cell-level tumour and host-cell patterns to metastasis and patient outcomes, providing a reference resource for lung cancer research.

## Timeline

- 2026-11-12: Study published online in Nature Cancer (doi:10.1038/s43018-026-01260-w)

## Coverage

- [A single-cell lung cancer atlas reveals cellular and molecular drivers of metastasis and clinical outcome](https://www.nature.com/articles/s43018-026-01260-w) — nature.com, 2026-11-12

Tags: lung cancer, single-cell sequencing, metastasis, spatial transcriptomics, tumour microenvironment

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Brief generated by AI (claude-haiku-5-5) from the reporting listed under Coverage. Headlines belong to their publishers. The Morning Science – https://themorning.science